Natural Products as A Promising Therapy for SARS COV-2; An Overview

Recently emerging pandemic SARS CoV-2 conquered our world since December 2019. Continuous efforts have been done to find out effective immunization and precise treatment stetratigies A way from therapeutic options that were tried in CoV-2, an increased attention is directed predict natural products mainly phytochemicals as collaborative measures for this crisis. In review, most of the mentioned compounds specially flavonoids (biacalin, hesperidin, quercetin, luteolin,, phenolic (resveratrol, curcumin, theaflavin) exert their effect through interfering with action one or more proteins (spike protein, papain like protease, 3 chymotrypsin cysteine RNA dependent 
 polymerase) are involved viral life cycle beside anti-inflammatory these compounds. The triterpenoids (celastrol, escin glycyrrhizin) alkaloids (lycorine cepharanthine) mediated activity. Glycyrrhetinic acid (glycyrrhizin metabolite) dawn regulates ACE 2, reduces protease expression, thus reduce entry. This review may be representing initial step long path designing successful vaccine pandemic.